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Low-grade fibromyxoid sarcoma (LGFMS) is a rare type of low grade sarcoma first described by Harry Evans in 1987. It is characterized by a long and indolent clinical course and the possibility of local recurrence or distant metastases in a subset of patients. Unlike many other types of cancer, low grade fibromyxoid sarcoma can metastasize after many years, sometimes decades after the initial presentation of the tumor. ==References== 〔 * Evans HL: Low-grade fibromyxoid sarcoma: a report of two metastasizing neoplasms having a deceptively benign appearance. Am J Clinical Pathology 1987, 88:615-619. * Goodlad JR, Mentzel T, Fletcher CD: Low grade fibromyxoid sarcoma: clinicopathological analysis of eleven new cases in support of a distinct entity. Histopathology 1995, 26(3):229-37. * Billings SD, Giblen G, Fanburg-Smith JC: Superficial low-grade fibromyxoid sarcoma (Evans tumor): a clinicopathologic analysis of 19 cases with a unique observation in the pediatric population. Am J Surg Pathol 2005, 29(2):204-10. * Zámecník M, Michal M: Low-grade fibromyxoid sarcoma: a report of eight cases with histologic, immunohistochemical, and ultrastructural study. Ann Diagn Pathol 2000, 4(4):207-17. * Evans HL: Low-grade fibromyxoid sarcoma. A report of 12 cases. Am J Surg Pathol 1993, 17(6):595-600. * Saito R, Kumabe T, Watanabe M, Jokura H, Shibuya M, Nakazato Y, Tominaga T: Low-grade fibromyxoid sarcoma of intracranial origin. J Neurosurg 2008, 108(4):798-802. * Tun K, Ozen O, Kaptanoglu E, et al.: Primary intracranial low-grade fibromyxoid sarcoma (Evans tumor). J Clin Neurosci 2008, 15(11):1298-301. * Jakowski JD, Wakely PE Jr: Primary intrathoracic low-grade fibromyxoid sarcoma. Hum Pathol 2008, 39(4):623-8. * Park IJ, Kim HC, Yu CS, Kim JS, Jang SJ, Kim JC: Low-grade fibromyxoid sarcoma of the colon. Dig Liver Dis 2007, 39(3):274-7. * Reid R, de Silva MV, Paterson L, Ryan E, Fisher C: Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes share a common t(7;16)(q34;p11) translocation. Am J Surg Pathol 2003, 27(9):1229-36. * Matsuyama A, Hisaoka M, Shimajiri S, Hayashi T, Imamura T, Ishida T, Fukunaga M, Fukuhara T, Minato H, Nakajima T, Yonezawa S, Kuroda M, Yamasaki F, Toyoshima S, Hashimoto H: Molecular detection of FUS- CREB3L2 fusion transcripts in low-grade fibromyxoid sarcoma using formalin-fixed, paraffin-embedded tissue specimens. Am J Surg Pathol 2006, 30(9):1077-84. * Folpe AL, Lane KL, Paull G, Weiss SW: Low-grade fibromyxoid sarcoma and hyalinizing spindle cell tumor with giant rosettes: a clinicopathologic study of 73 cases supporting their identity and assessing the impact of high-grade areas. Am J Surg Pathol 2000, 24:1353-1360. * Guillou L, Benhattar J, Gengler C, Gallagher G, Ranche?re-Vince D, Collin F, Terrier P, Terrier-Lacombe MJ, Leroux A, Marque?s B, Aubain Somerhausen Nde S, Keslair F, Pedeutour F, Coindre JM: Translocation-positive low- grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group. Am J Surg Pathol 2007, 31(9):1387-402. * Mertens F, Fletcher CD, Antonescu CR, Coindre JM, Colecchia M, Domanski HA, Downs-Kelly E, Fisher C, Goldblum JR, Guillou L, Reid R, Rosai J, Sciot R, Mandahl N, Panagopoulos I: Clinicopathologic and molecular genetic characterization of low-grade fibromyxoid sarcoma, and cloning of a novel FUS/CREB3L1 fusion gene. Lab Invest 2005, 85(3):408-15. * Panagopoulos I, Storlazzi CT, Fletcher CD, Fletcher JA, Nascimento A, Domanski HA, Wejde J, Brosjö, Rydholm A, Isaksson M, Mandahl N, Mertens F: The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma. Genes Chromosomes Cancer 2004, 40(3):218-28. * Storlazzi CT, Mertens F, Nascimento A, Isaksson M, Wejde J, Brosjo O, Mandahl N, Panagopoulos I: Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma. Hum Mol Genet 2003, 12(18):2349-58. * Vernon SE, Bejarano PA: Low-grade fibromyxoid sarcoma: a brief review. Arch Pathol Lab Med 2006, 130(9):1358-60. * Matsuyama A, Hisaoka M, Shimajiri S, Hashimoto H: DNA-based polymerase chain reaction for detecting FUS-CREB3L2 in low-grade fibromyxoid sarcoma using formalin-fixed, paraffin-embedded tissue specimens. Diagn Mol Pathol 2008, 17(4):237-40. * Folpe A, van den Berg E, Molenaar WM: Low grade fibromyxoid sarcoma. In World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Edited by: Fletcher CDM, Unni KK, Mertens F. IARC Press: Lyon; 2002:104-5. * Panagopoulos I, Möller E, Dahlén A, Dahlén A, Isaksson M, Mandahl N, Vlamis-Gardikas A, Mertens F: Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera. Genes Chromosomes Cancer 2007, 46(2):181-91. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Low-grade fibromyxoid sarcoma」の詳細全文を読む スポンサード リンク
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